Based on the popular 'Southern Vampire,' book series by Charlaine Harris, "True Blood" follows the adventures of a small-town cocktail waitress Sookie Stackhouse (who all her life was an outsider due to her gift/curse of being a telepath) and how her life is turned upside down when a member of the undead (the vampire race 'came out of the coffin' several years earlier) walks into her life one fateful night.

Sam tests the strength of his family bonds. Tara finds an ally in a shady vampire named Franklin Mott. Eric remembers his past. Russell Edgington, the Vampire King of Mississippi, concocts a plan to consolidate his power.